Impaired Cholecystokinin - Induced Gallbladder Emptying
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منابع مشابه
Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice.
"Black" pigment gallstones form in sterile gallbladder bile in the presence of excess bilirubin conjugates ("hyperbilirubinbilia") from ineffective erythropoiesis, hemolysis, or induced enterohepatic cycling (EHC) of unconjugated bilirubin. Impaired gallbladder motility is a less well-studied risk factor. We evaluated the spontaneous occurrence of gallstones in adult germfree (GF) and conventio...
متن کاملRole of intraduodenal proteases in plasma cholecystokinin and pancreaticobiliary responses to protein and amino acids.
BACKGROUND & AIMS The role of small intestinal proteolytic activity in the regulation of upper gastrointestinal function in humans is poorly understood. The aim of this study was to determine the importance of proteolytic activity for protein- or amino acid-induced cholecystokinin release and pancreaticobiliary secretion. METHODS In 9 healthy subjects, saline was perfused intraduodenally for ...
متن کاملCholestyramine influences meal-stimulated pancreaticobiliary function and plasma cholecystokinin independent of gastric emptying and food digestion.
BACKGROUND Cholestyramine enhances gallbladder emptying and plasma cholecystokinin responses to oral ingestion of a mixed meal. It is not known whether this effect occurs independently of alterations in gastric emptying or maldigestion of nutrients. METHODS We perfused 15 g of an amino acid meal intraduodenally for 60 min in seven healthy volunteers, once with and once without cholestyramine....
متن کاملThe Effect of Breast Feeding on Plasma Cholecystokinin in Neonates
Cholecystokinin (CCK), a gastrointestinal hormone, is secreted by the duodenum in response to the presence of gastric acid, amino acids and nutrients in particular fat in the duodenal lumen (1). The half life of this hormone is about 2.5 minutes and the kidney is considered the major site of its uptake from the systemic circulation. Cholecystokinin is responsible for stimulating gallbladder con...
متن کاملGall bladder emptying in severe idiopathic constipation.
BACKGROUND It has been suggested that slow transit constipation (STC) may be part of a panenteric motor disorder. AIM To evaluate motility of an upper gastrointestinal organ, the gall bladder, in 16 patients with STC and 20 healthy controls. METHODS Gall bladder emptying (ultrasonography) was studied in response to neural, cephalic-vagal stimulation with modified sham feeding (MSF) for 90 m...
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تاریخ انتشار 2015